Opioid Constipation Clinical Trial

KRK Medical Research is seeking volunteers to participate in a clinical research study to evaluate the effectiveness of an investigational medication for treatment of constipation due to opioid use.

This is a national study sponsored by Wyeth Pharmaceuticals. The study is conducted by Andrew M. Klymiuk, M.D. with Gloria Cha, M.D. and
Jadwiga Klymiuk, M.D. as sub-investigators. Our medical research clinic is located in Dallas, Texas.

In order to qualify you must meet the following criteria:
• Male or female over the age of 18.
• Suffering constipation due to narcotic use for pain management.
• Have been taking narcotic medication for at least 1 month (for example: Vicodin, Lortab, Lorcet, MS Contin, OxyContin, Dilaudud, Duragesic, Actiq, methadone, codeine, etc.).

Participation Duration: The study can last up to 17 weeks and requires 14 visits.

All study related medical procedures, physical examinations, physician visits, laboratory tests and investigational medication are at no charge. No health insurance is needed. You may also receive compensation for your time and travel.

Please email us below if you would like to receive more information about this study. We will contact you by phone or email within 24 hours. Be assured that all information is kept strictly confidential per HIPAA regulations, FDA laws and the American Medical Association ethical guidelines.


If you would like to receive more information about the Opioid Constipation Clinical Trial, please Click Here and email your name and phone number to receive a response from one of our nurse research coordinators.

You may also call one of our nurses at 972-907-1333.